Galaxolide

Aroma chemical · Musky / Floral

musky, clean, sweet, floral, powdery — base note.

Aroma illustration for Galaxolide: soft white clouds, soap bubbles and pink flowers, for its musky, clean and floral notes. It illustrates smell associations, not the material or its source.Skeletal formula of Galaxolide, C18H26O, drawn from PubChem's 2D record. Stereochemistry is not shown.
Aroma View: an illustration of what Galaxolide smells like (musky, clean, floral), drawn by RUŌOD Lab — not its appearance or its source.Skeletal formula drawn by RUŌOD Lab from PubChem's 2D record (CID 91497). Stereochemistry is not shown; the coloured background is decoration.
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By the RUŌOD Lab TeamRevision 1Updated

In short

Galaxolide (HHCB) is a polycyclic musk from IFF and one of the most used musks in the world, especially in laundry and personal-care fragrance. It gives a clean, sweet, floral musk.

What Galaxolide smells like

Galaxolide (HHCB) is a polycyclic musk usually described as the sweeter, cleaner one beside Tonalide; supplier glossaries contrast Tonalide's drier, more powdery, amber-woody character with Galaxolide's sweetness, and another finds Celestolide less aggressive than Galaxolide. Its 'clean' impression is the laundry-like musk of washing products. Few direct descriptions of Galaxolide alone were found.

Leading note
Clean sweet musk
Supporting facets
Floral, powdery
Character
Clean, soft, diffusive, tenacious
  • musky
  • clean
  • sweet
  • floral
  • powdery

What makes Galaxolide distinctive

The clean-laundry musk: sweet and floral, the musk most people know from washing powder.

How Galaxolide is used

Used very widely in functional products, laundry care and fine fragrance as a clean, sweet musk base.

Typical role: backbone (used in large proportions as a structural material of an accord); fixative (slow to evaporate; helps a blend last and holds lighter notes).

How Galaxolide differs from similar materials

Tonalide
Tonalide is drier and more powdery, with a light amber-woody base and less sweetness; Galaxolide is the sweeter, cleaner musk. (compared directly by a cited source)
Celestolide
A glossary finds Celestolide less aggressive than Galaxolide, clean and sweet with a slight fruity-floral note. (compared directly by a cited source)
Habanolide
Habanolide, a macrocycle, adds a hot-iron metallic facet to a clean white musk; Galaxolide is sweeter and more floral.

An asterisk marks a difference that a cited source states directly. The others compare the published descriptions of each material. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.

Formulation considerations

Pure Galaxolide is extremely viscous, so it is usually sold diluted, commonly at 50% in a solvent such as isopropyl myristate or benzyl benzoate — record the dilution, because it changes every calculation. Its environmental persistence is under regulatory scrutiny in some markets.

Identity and classification

Type
Aroma chemical
Origin
Synthetic
Odour family
Musky / Floral
Note position
Base note
Physical form at room temperature
Viscous liquid
Also known as
HHCB
CAS number
1222-05-5
Molecular formula
C18H26O
Molecular weight
258.4 g/mol
IUPAC name
4,6,6,7,8,8-hexamethyl-1,3,4,7-tetrahydrocyclopenta[g]isochromene

The CAS number, formula and molecular weight are taken from PubChem compound 91497, whose own record lists this CAS number; checked 19 October 2026.

Safety and compliance

Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. It has a harmonised EU classification (Regulation (EC) No 1272/2008, Annex VI): H400 very toxic to aquatic life; H410 very toxic to aquatic life with long lasting effects. Companies notifying the ECHA C&L Inventory classify it (2,093 reports): H410 very toxic to aquatic life with long lasting effects (100% of reports); H400 very toxic to aquatic life (97.9% of reports). Unless it is harmonised, this is the notifiers' own classification, not a binding one.

This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.

Materials it works with

Galaxolide is also suggested as a partner on the pages for Applelide, Cyclohexyl Salicylate, Musk Ketone, Traseolide, Velvione and Zenolide.

Used in formulas and accords

Used in 67 published formulas

Galaxolide is an ingredient in 39 perfume formulas and 28 accords in the Formula & Accord Library.

Community formulas

RUŌOD House Originals

Original compositions by RUŌOD House.

Further reading

Questions about Galaxolide

Is Galaxolide natural or synthetic?

Galaxolide is synthetic — it is made by chemical synthesis.

What is the CAS number of Galaxolide?

1222-05-5. It was checked against PubChem on 19 October 2026.

Which published formulas use Galaxolide?

Galaxolide is used in 67 published formulas in the RUŌOD Lab Formula & Accord Library, including Açaí Accord, Amber Accord and Anise Ink. Each is listed with a link under "Used in formulas and accords" on this page.

Sources

Your own records, next to the reference

Keep your own record of Galaxolide — supplier, cost, stock, dilutions and where it is used — in RUŌOD Lab's material library.