Tonalide

Aroma chemical · Musky / Powdery

musky, powdery, sweet, woody — base note.

Aroma illustration for Tonalide: soft white clouds, a powder puff and fine powder and a cut log, for its musky, powdery and woody notes. It illustrates smell associations, not the material or its source.Skeletal formula of Tonalide, C18H26O, drawn from PubChem's 2D record. Stereochemistry is not shown.
Aroma View: an illustration of what Tonalide smells like (musky, powdery, woody), drawn by RUŌOD Lab — not its appearance or its source.Skeletal formula drawn by RUŌOD Lab from PubChem's 2D record (CID 89440). Stereochemistry is not shown; the coloured background is decoration.
Images

By the RUŌOD Lab TeamRevision 1Updated

In short

Tonalide (AHTN) is a polycyclic musk with a sweet, powdery, slightly woody musk note, long used in functional fragrance.

What Tonalide smells like

Tonalide (AHTN) is a polycyclic musk with more powdery softness and less sweetness than Galaxolide, anchored by a light amber-woody undertone, in a supplier glossary; another source calls it sweet woody-musky with considerable tenacity, and another musky-sweet, slightly mineral or crystalline, with dry, woody, ambery and dusty facets. It is often associated with clean-laundry accords.

Leading note
Powdery musk
Supporting facets
Woody, amber, sweet
Faint facets
Mineral, dusty
Character
Powdery, dry, tenacious
  • musky
  • powdery
  • sweet
  • woody

What makes Tonalide distinctive

The drier polycyclic musk: powder and amber-wood where Galaxolide is sweet and floral.

How Tonalide is used

Used as a powdery musk base in functional and fine fragrance.

Typical role: fixative (slow to evaporate; helps a blend last and holds lighter notes).

How Tonalide differs from similar materials

Galaxolide
Galaxolide is sweeter and cleaner; Tonalide is drier and more powdery, with an amber-woody base. (compared directly by a cited source)
Traseolide
Traseolide is warmer and more golden, closer to the old nitro musks; Tonalide is drier and more powdery.
Musk Ketone
Musk ketone is sweeter and more powdery, with a discreet animal note; Tonalide is drier and woodier.
Celestolide
A glossary finds Celestolide less powdery than Tonalide, clean and sweet with a slight fruity-floral note. (compared directly by a cited source)

An asterisk marks a difference that a cited source states directly. The others compare the published descriptions of each material. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.

Formulation considerations

A solid; dissolve before use. Its use in cosmetics is restricted in the EU, so check market rules.

Identity and classification

Type
Aroma chemical
Origin
Synthetic
Odour family
Musky / Powdery
Note position
Base note
Physical form at room temperature
Solid
Also known as
AHTN
CAS number
21145-77-7
Molecular formula
C18H26O
Molecular weight
258.4 g/mol
IUPAC name
1-(3,5,5,6,8,8-hexamethyl-6,7-dihydronaphthalen-2-yl)ethanone

The CAS number, formula and molecular weight are taken from PubChem compound 89440, whose own record lists this CAS number; checked 19 October 2026.

Safety and compliance

Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. Companies notifying the ECHA C&L Inventory classify it (1,807 reports): H410 very toxic to aquatic life with long lasting effects (97.9% of reports); H302 harmful if swallowed (97.7% of reports); H400 very toxic to aquatic life (90.7% of reports). 38 of the reports find it does not meet the hazard criteria. Unless it is harmonised, this is the notifiers' own classification, not a binding one.

This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.

Materials it works with

Tonalide is also suggested as a partner on the pages for Celestolide and Traseolide.

Used in formulas and accords

Used in 14 published formulas

Tonalide is an ingredient in 5 perfume formulas, 8 accords and 1 base in the Formula & Accord Library.

Community formulas

RUŌOD House Originals

Original compositions by RUŌOD House.

Further reading

Questions about Tonalide

Is Tonalide natural or synthetic?

Tonalide is synthetic — it is made by chemical synthesis.

What is the CAS number of Tonalide?

21145-77-7. It was checked against PubChem on 19 October 2026.

Which published formulas use Tonalide?

Tonalide is used in 14 published formulas in the RUŌOD Lab Formula & Accord Library, including Banana Bread, Blackberry Accord and Carnation Accord. Each is listed with a link under "Used in formulas and accords" on this page.

Sources

  • PubChem — compound 89440, checked 19 October 2026.
  • PubChem — GHS classification (the ECHA C&L Inventory notifications and any harmonised EU entry), read 26 October 2026.
  • Premiere Peau — Tonalide — published perfumery reference.
  • Scentspiracy — What is Tonalide? — distributor's description.
  • EvitaChem — Tonalid — distributor's description.
  • Olfactory profile: the RUŌOD Lab team's synthesis of the published descriptions above, reviewed 21 October 2026. Evidence: more than one published description. Classification and the short description: revision 1. Descriptions of odour are judgement, not measurement.

Your own records, next to the reference

Keep your own record of Tonalide — supplier, cost, stock, dilutions and where it is used — in RUŌOD Lab's material library.