In short
Cosmone is a trade name for a macrocyclic ketone musk with a warm, powdery and slightly animalic character. It is powerful and diffusive for a musk.
What Cosmone smells like
Cosmone (Givaudan) is a very rich, intense and diffusive musky note with warm and powdery facets, reminiscent of ambergris, with sweet aspects of nitro musks, in Givaudan's description. Third-party descriptions add anisic and faintly fruity nuances. A forum thread claims it was discontinued, which was not confirmed by Givaudan.
- Leading note
- Rich warm musk
- Supporting facets
- Powdery, ambergris
- Faint facets
- Anisic
- Character
- Rich, intense, diffusive
What makes Cosmone distinctive
A rich macrocyclic musk with an ambergris glow and the sweetness of the old nitro musks.
How Cosmone is used
Used as a rich, diffusive musk in fine fragrance and amber compositions.
Typical role: fixative (slow to evaporate; helps a blend last and holds lighter notes); modifier (used in small amounts to change the character of a blend).
How Cosmone differs from similar materials
- Muscenone
- Muscenone is more animal; Cosmone is richer, with ambergris and warm powder.
- Velvione
- Velvione is a powdery macrocyclic musk with animalic, civet-like aspects; Cosmone is warmer, with ambergris.
Each difference compares the published descriptions of the two materials. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.
Identity and classification
- Type
- Aroma chemical
- Origin
- Synthetic
- Odour family
- Musky / Animalic
- Note position
- Base note
- Physical form at room temperature
- Liquid
- Also known as
- (Z)-3-Methylcyclotetradec-5-en-1-one
- CAS number
- 259854-70-1
- Molecular formula
- C15H26O
- Molecular weight
- 222.37 g/mol
- IUPAC name
- (5E)-3-methylcyclotetradec-5-en-1-one
The CAS number, formula and molecular weight are taken from PubChem compound 66823518, whose own record lists this CAS number; checked 19 October 2026.
Safety and compliance
Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. Companies notifying the ECHA C&L Inventory classify it (220 reports): H317 may cause an allergic skin reaction (100% of reports); H410 very toxic to aquatic life with long lasting effects (85.9% of reports); H400 very toxic to aquatic life (65.9% of reports); H302 harmful if swallowed (14.1% of reports); H373 may causes damage to organs through prolonged or repeated exposure (14.1% of reports). A skin sensitiser classification concerns handling the neat material and the dose in a finished product; the IFRA Standards, where they apply, set the limits. Unless it is harmonised, this is the notifiers' own classification, not a binding one.
This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.
Materials it works with
Used in formulas and accords
Used in 23 published formulas
Cosmone is an ingredient in 21 perfume formulas, 1 accord and 1 base in the Formula & Accord Library.
Community formulas
RUŌOD House Originals
Original compositions by RUŌOD House.
Further reading
Questions about Cosmone
Is Cosmone natural or synthetic?
Cosmone is synthetic — it is made by chemical synthesis.
What is the CAS number of Cosmone?
259854-70-1. It was checked against PubChem on 19 October 2026.
Which published formulas use Cosmone?
Cosmone is used in 23 published formulas in the RUŌOD Lab Formula & Accord Library, including Apple Cellar, Beeswax Throne and Black Saddle. Each is listed with a link under "Used in formulas and accords" on this page.
Sources
- PubChem — compound 66823518, checked 19 October 2026.
- PubChem — GHS classification (the ECHA C&L Inventory notifications and any harmonised EU entry), read 26 October 2026.
- Givaudan — Cosmone — manufacturer's description.
- The Good Scents Company — Cosmone — odour database.
- Basenotes — Thoughts on Cosmone (forum) — published perfumery reference.
- Olfactory profile: the RUŌOD Lab team's synthesis of the published descriptions above, reviewed 21 October 2026. Evidence: more than one published description. Classification and the short description: revision 1. Descriptions of odour are judgement, not measurement.








