Canthoxal

Aroma chemical · Floral / Green

anisic, sweet, liquorice, herbal, floral — heart note.

Aroma illustration for Canthoxal: star anise, white hawthorn blossoms and green leaves, for its anisic, hawthorn and green notes. It illustrates smell associations, not the material or its source.Skeletal formula of Canthoxal (Anisyl propanal), C11H14O2, drawn from PubChem's 2D record. Stereochemistry is not shown.
Aroma View: an illustration of what Canthoxal smells like (anisic, hawthorn, green), drawn by RUŌOD Lab — not its appearance or its source.Skeletal formula drawn by RUŌOD Lab from PubChem's 2D record (CID 64813). Stereochemistry is not shown; the coloured background is decoration.
Images

By the RUŌOD Lab TeamRevision 2Updated

In short

Canthoxal is a trade name for 2-methyl-3-(4-methoxyphenyl)propanal, an aromatic aldehyde with a sweet anisic odour and liquorice, basil and fennel facets.

What Canthoxal smells like

Canthoxal (IFF; anisyl propanal) is an anise-type aldehyde. IFF describes licorice, basil, fennel and anise notes with a slight fruity and watery modification; suppliers list anisic, balsamic, basil, fennel, floral, herbal and licorice, and floral, anisic, balsamic and spicy. A distributor describes a soft, sweet anisic character with delicate watery, transparent qualities. On its own it can seem dull.

Leading note
Sweet anise
Clear facets
Licorice
Supporting facets
Basil, fennel, watery
Faint facets
Floral
Character
Soft, sweet, transparent, herbal
  • anisic
  • sweet
  • liquorice
  • herbal
  • floral

What makes Canthoxal distinctive

A watery, herbal anise — licorice, basil and fennel in a transparent aldehyde, rather than the powdery hawthorn of anisaldehyde.

How Canthoxal is used

Used for anisic and herbal-floral effects; its Schiff base with methyl anthranilate is the hawthorn-mimosa material often associated with it.

Typical role: modifier (used in small amounts to change the character of a blend); blender (smooths the joins between other materials).

How Canthoxal differs from similar materials

Anisaldehyde
Anisaldehyde is sweet hawthorn and mimosa; Canthoxal is a watery licorice-basil-fennel anise.
Anethole
Anethole is the sweet licorice-anise itself, warmer and denser; Canthoxal is more transparent and herbal, with basil and fennel.

Each difference compares the published descriptions of the two materials. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.

Formulation considerations

An aldehyde: it can discolour or react in some bases, so test stability in the final product.

Identity and classification

Type
Aroma chemical
Origin
Synthetic
Odour family
Floral / Green
Note position
Heart note
Physical form at room temperature
Liquid
Also known as
Anisyl propanal, 2-Methyl-3-(4-methoxyphenyl)propanal
CAS number
5462-06-6
Molecular formula
C11H14O2
Molecular weight
178.23 g/mol
IUPAC name
3-(4-methoxyphenyl)-2-methylpropanal

The CAS number, formula and molecular weight are taken from PubChem compound 64813, whose own record lists this CAS number; checked 19 October 2026.

Safety and compliance

The IFRA Standards Library lists a Standard covering Canthoxal:

  • "4-Methoxy-alpha-methylbenzenepropanal" — Restriction, 51st Amendment, published 2023-06

Limits differ by product category and are set out in the Standard itself; this page does not reproduce them. The list above reflects the library as read on 19 October 2026.

Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. Companies notifying the ECHA C&L Inventory classify it (1,748 reports): H317 may cause an allergic skin reaction (99.8% of reports); H412 harmful to aquatic life with long lasting effects (87.9% of reports); H319 causes serious eye irritation (73.8% of reports). 3 of the reports find it does not meet the hazard criteria. A skin sensitiser classification concerns handling the neat material and the dose in a finished product; the IFRA Standards, where they apply, set the limits. Unless it is harmonised, this is the notifiers' own classification, not a binding one.

This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.

Materials it works with

Canthoxal is also suggested as a partner on the pages for Anisyl Acetate.

Used in formulas and accords

Used in 2 published formulas

Canthoxal is an ingredient in 1 perfume formula and 1 accord in the Formula & Accord Library.

Community formulas

RUŌOD House Originals

Original compositions by RUŌOD House.

Further reading

Questions about Canthoxal

Is Canthoxal natural or synthetic?

Canthoxal is synthetic — it is made by chemical synthesis.

What is the CAS number of Canthoxal?

5462-06-6. It was checked against PubChem on 19 October 2026.

Which published formulas use Canthoxal?

Canthoxal is used in 2 published formulas in the RUŌOD Lab Formula & Accord Library: Anise Ink and Hyacinth Accord. Each is listed with a link under "Used in formulas and accords" on this page.

Is Canthoxal covered by an IFRA Standard?

Yes. The IFRA Standards Library lists a Standard covering it: "4-Methoxy-alpha-methylbenzenepropanal" — Restriction, 51st Amendment. The limits depend on the product category; read the Standard itself before formulating.

Sources

Your own records, next to the reference

Keep your own record of Canthoxal — supplier, cost, stock, dilutions and where it is used — in RUŌOD Lab's material library.