Sulfurol

Aroma chemical · Gourmand

beefy, nutty — heart to base note.

Aroma illustration for Sulfurol: hazelnuts, for its nutty note. It illustrates smell associations, not the material or its source.Skeletal formula of Sulfurol (4-Methyl-5-thiazoleethanol), C6H9NOS, drawn from PubChem's 2D record. Stereochemistry is not shown.
Aroma View: an illustration of what Sulfurol smells like (nutty), drawn by RUŌOD Lab — not its appearance or its source.Skeletal formula drawn by RUŌOD Lab from PubChem's 2D record (CID 1136). Stereochemistry is not shown; the coloured background is decoration.
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By the RUŌOD Lab TeamRevision 1Updated

In short

Sulfurol is a sulphur-containing thiazole found in cooked and fermented foods. JECFA describes its odour as beefy and nutty.

What Sulfurol smells like

JECFA, the joint FAO/WHO committee that evaluates flavouring substances, describes sulfurol as a colourless to pale yellow viscous oily liquid with a beefy, nutty odour that may darken on ageing. Fraterworks describes a creamy, warm, lactonic aroma with subtle roasted undertones and a soft, sweet dairy character.

Leading note
Beefy
Clear facets
Nutty
Character
Savoury
  • beefy
  • nutty

What makes Sulfurol distinctive

A cooked-meat, nutty note — savoury rather than sweet, which sets it apart from the roasted-sweet pyrazines.

Concentration and dilution

Fraterworks sells it pure and at 10% in DPG because of its strength, and advises waiting at least 24 hours between additions.

How Sulfurol is used

Fraterworks uses it to enhance milky accords in gourmand fragrances and to add creaminess to vanilla, coconut and dessert compositions.

Typical role: modifier (used in small amounts to change the character of a blend).

How Sulfurol differs from similar materials

4-Methyl-5-vinylthiazole
Vinyl sulfurol, its vinyl relative, is described as nutty and cocoa-like rather than beefy.

Each difference compares the published descriptions of the two materials. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.

Formulation considerations

May darken as it ages, according to JECFA. Very food-like; work from dilution.

Identity and classification

Type
Aroma chemical
Origin
Occurs in nature
Odour family
Gourmand
Note position
Heart to base note
Physical form at room temperature
Viscous liquid
Also known as
4-Methyl-5-thiazoleethanol, 4-Methyl-5-(2-hydroxyethyl)thiazole
CAS number
137-00-8
Molecular formula
C6H9NOS
Molecular weight
143.21 g/mol
IUPAC name
2-(4-methyl-1,3-thiazol-5-yl)ethanol

The CAS number, formula and molecular weight are taken from PubChem compound 1136, whose own record lists this CAS number; checked 24 October 2026.

Safety and compliance

Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. Companies notifying the ECHA C&L Inventory classify it (424 reports): H315 causes skin irritation (17.2% of reports); H319 causes serious eye irritation (17.2% of reports); H335 may cause respiratory irritation (17% of reports). 350 of the reports find it does not meet the hazard criteria. Unless it is harmonised, this is the notifiers' own classification, not a binding one.

This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.

Materials it works with

Sulfurol is also suggested as a partner on the pages for 2-Ethyl-4-methylthiazole, 4-Methyl-5-vinylthiazole, Butter CO2 Extract and Difurfuryl Disulfide.

Used in formulas and accords

Used in 8 published formulas

Sulfurol is an ingredient in 1 perfume formula and 7 accords in the Formula & Accord Library.

Further reading

Questions about Sulfurol

Is Sulfurol natural or synthetic?

The molecule occurs in nature. Commercial Sulfurol may be made by synthesis or obtained from natural sources, so check the supplier's specification if the distinction matters to you.

What is the CAS number of Sulfurol?

137-00-8. It was checked against PubChem on 24 October 2026.

Which published formulas use Sulfurol?

Sulfurol is used in 8 published formulas in the RUŌOD Lab Formula & Accord Library, including Banana Bread, Cappuccino Accord and Cookies & Cream Accord. Each is listed with a link under "Used in formulas and accords" on this page.

Sources

Your own records, next to the reference

Keep your own record of Sulfurol — supplier, cost, stock, dilutions and where it is used — in RUŌOD Lab's material library.