Prenyl Mercaptan

Aroma chemical · Green

sulphurous, skunky, onion, leek — top note.

Aroma illustration for Prenyl Mercaptan: an abstract yellow-green haze, for its sulphurous note. It illustrates smell associations, not the material or its source.Skeletal formula of Prenyl Mercaptan (3-Methyl-2-butene-1-thiol), C5H10S, drawn from PubChem's 2D record. Stereochemistry is not shown.
Aroma View: an illustration of what Prenyl Mercaptan smells like (sulphurous), drawn by RUŌOD Lab — not its appearance or its source.Skeletal formula drawn by RUŌOD Lab from PubChem's 2D record (CID 146586). Stereochemistry is not shown; the coloured background is decoration.
Images

By the RUŌOD Lab TeamRevision 1Updated

In short

Prenyl mercaptan is 3-methyl-2-butene-1-thiol, an extremely potent sulphur compound with a skunky, leek-like odour. It is the compound behind light-struck beer.

What Prenyl Mercaptan smells like

The Good Scents Company describes prenyl mercaptan as sulphurous, with intense leek, onion-like and skunky notes. A supplier reports an extremely low odour threshold and notes that the free thiol oxidises readily to the disulfide. PubChem links it to natural-product and yeast-metabolome databases.

Leading note
Skunky
Clear facets
Leek
Supporting facets
Onion
Character
Sulphurous, potent
  • sulphurous
  • skunky
  • onion
  • leek

What makes Prenyl Mercaptan distinctive

The skunk note itself, effective at traces.

How Prenyl Mercaptan is used

Used at trace dilutions for cannabis, coffee and blackcurrant effects.

Typical role: modifier (used in small amounts to change the character of a blend).

How Prenyl Mercaptan differs from similar materials

Difurfuryl Disulfide
Difurfuryl disulfide is the roasted-coffee, meaty sulphur; prenyl mercaptan is raw, skunky and alliaceous.
Dimethyl Sulfide
Dimethyl sulfide is the cabbage-and-radish sulphur; prenyl mercaptan is skunkier and more alliaceous.

Each difference compares the published descriptions of the two materials. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.

Formulation considerations

Extremely potent and prone to oxidise; handle as a high dilution.

Identity and classification

Type
Aroma chemical
Origin
Occurs in nature
Odour family
Green
Note position
Top note
Physical form at room temperature
Liquid
Also known as
3-Methyl-2-butene-1-thiol
CAS number
5287-45-6
Molecular formula
C5H10S
Molecular weight
102.2 g/mol
IUPAC name
3-methylbut-2-ene-1-thiol

The CAS number, formula and molecular weight are taken from PubChem compound 146586, whose own record lists this CAS number; checked 24 October 2026.

Safety and compliance

Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. Companies notifying the ECHA C&L Inventory classify it (160 reports): H226 flammable liquid and vapor (100% of reports); H315 causes skin irritation (75% of reports); H319 causes serious eye irritation (75% of reports); H335 may cause respiratory irritation (75% of reports); H302 harmful if swallowed (26.2% of reports). Unless it is harmonised, this is the notifiers' own classification, not a binding one.

This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.

Materials it works with

Used in formulas and accords

Used in 1 published formula

Prenyl Mercaptan is an ingredient in 1 base in the Formula & Accord Library.

Further reading

Questions about Prenyl Mercaptan

Is Prenyl Mercaptan natural or synthetic?

The molecule occurs in nature. Commercial Prenyl Mercaptan may be made by synthesis or obtained from natural sources, so check the supplier's specification if the distinction matters to you.

What is the CAS number of Prenyl Mercaptan?

5287-45-6. It was checked against PubChem on 24 October 2026.

Which published formulas use Prenyl Mercaptan?

Prenyl Mercaptan is used in 1 published formula in the RUŌOD Lab Formula & Accord Library: Cannabis Base. Each is listed with a link under "Used in formulas and accords" on this page.

Sources

  • PubChem — compound 146586, checked 24 October 2026.
  • PubChem — GHS classification (the ECHA C&L Inventory notifications and any harmonised EU entry), read 26 October 2026.
  • The Good Scents Company — prenyl mercaptan — odour database.
  • Smolecule — prenyl mercaptan — distributor's description.
  • Olfactory profile: the RUŌOD Lab team's synthesis of the published descriptions above, reviewed 26 October 2026. Evidence: more than one published description. Classification and the short description: revision 1. Descriptions of odour are judgement, not measurement.

Your own records, next to the reference

Keep your own record of Prenyl Mercaptan — supplier, cost, stock, dilutions and where it is used — in RUŌOD Lab's material library.