Lyral

Aroma chemical · Floral

muguet, lily, cyclamen, floral, soft — heart note.

Aroma illustration for Lyral: lily of the valley bells, for its muguet note. It illustrates smell associations, not the material or its source.Skeletal formula of Lyral (Hydroxyisohexyl 3-cyclohexene carboxaldehyde), C13H22O2, drawn from PubChem's 2D record. Stereochemistry is not shown.
Aroma View: an illustration of what Lyral smells like (muguet), drawn by RUŌOD Lab — not its appearance or its source.Skeletal formula drawn by RUŌOD Lab from PubChem's 2D record (CID 91604). Stereochemistry is not shown; the coloured background is decoration.
Images

By the RUŌOD Lab TeamRevision 1Updated

In short

Lyral (HICC) is the muguet aldehyde IFF introduced in 1958, once among the most used floral materials. It is now prohibited in cosmetic products in the EU.

What Lyral smells like

The Good Scents Company quotes IFF's description of Lyral as a soft, delicate floral, lily, cyclamen and lilac note reminiscent of hydroxycitronellal, with strong tenacity; another listing gives floral, muguet, aldehydic and woody. A patent cites it as an IFF ingredient valued for its lily-of-the-valley note. Its EU status is taken from Regulation (EU) 2017/1410 as recorded in this site's regulatory notes.

Leading note
Muguet
Clear facets
Lily
Supporting facets
Cyclamen, lilac
Character
Soft, tenacious
  • muguet
  • lily
  • cyclamen
  • floral
  • soft

What makes Lyral distinctive

The classic soft muguet aldehyde, now historical in EU cosmetics.

How Lyral is used

Formerly a backbone of muguet and white-floral accords; historic formulas name it, current EU cosmetics may not contain it.

Typical role: backbone (used in large proportions as a structural material of an accord).

How Lyral differs from similar materials

Lilial
Lilial, the other muguet aldehyde now prohibited in EU cosmetics, is more radiant, green and aldehydic-clean.

Each difference compares the published descriptions of the two materials. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.

Formulation considerations

Prohibited in cosmetic products in the European Union: Annex II, entry 1380 (Regulation (EU) 2017/1410), not to be placed on the market from 23 August 2019 or made available from 23 August 2021. IFRA restricts it (Amendment 49). It is a known skin sensitiser.

Identity and classification

Type
Aroma chemical
Origin
Synthetic
Odour family
Floral
Note position
Heart note
Physical form at room temperature
Viscous liquid
Also known as
HICC, Hydroxyisohexyl 3-cyclohexene carboxaldehyde
CAS number
31906-04-4
Molecular formula
C13H22O2
Molecular weight
210.31 g/mol
IUPAC name
4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde

The CAS number, formula and molecular weight are taken from PubChem compound 91604, whose own record lists this CAS number; checked 24 October 2026.

Safety and compliance

The IFRA Standards Library lists a Standard covering Lyral:

  • "3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (HMPCC)" — Restriction, 49th Amendment, published 2020-01

Limits differ by product category and are set out in the Standard itself; this page does not reproduce them. The list above reflects the library as read on 19 October 2026.

Lyral is one of the 26 fragrance allergens listed individually in Annex III of the EU Cosmetics Regulation (label name: Hydroxyisohexyl 3-cyclohexene carboxaldehyde), which must be named on cosmetic labels above 0.001% in leave-on and 0.01% in rinse-off products. Regulation (EU) 2023/1545 extended the list; see the fragrance allergens list.

Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. It has a harmonised EU classification (Regulation (EC) No 1272/2008, Annex VI): H317 may cause an allergic skin reaction. Companies notifying the ECHA C&L Inventory classify it (1,981 reports): H317 may cause an allergic skin reaction (97.9% of reports); H412 harmful to aquatic life with long lasting effects (15.1% of reports). 41 of the reports find it does not meet the hazard criteria. A skin sensitiser classification concerns handling the neat material and the dose in a finished product; the IFRA Standards, where they apply, set the limits. Unless it is harmonised, this is the notifiers' own classification, not a binding one.

This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.

Materials it works with

Used in formulas and accords

Not currently used in any published formula.

The Formula & Accord Library lists Lyral here as soon as a published formula, accord or base uses it.

Further reading

Questions about Lyral

Is Lyral natural or synthetic?

Lyral is synthetic — it is made by chemical synthesis.

What is the CAS number of Lyral?

31906-04-4. It was checked against PubChem on 24 October 2026.

Is Lyral covered by an IFRA Standard?

Yes. The IFRA Standards Library lists a Standard covering it: "3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (HMPCC)" — Restriction, 49th Amendment. The limits depend on the product category; read the Standard itself before formulating.

Sources

Your own records, next to the reference

Keep your own record of Lyral — supplier, cost, stock, dilutions and where it is used — in RUŌOD Lab's material library.