In short
Lyral (HICC) is the muguet aldehyde IFF introduced in 1958, once among the most used floral materials. It is now prohibited in cosmetic products in the EU.
What Lyral smells like
The Good Scents Company quotes IFF's description of Lyral as a soft, delicate floral, lily, cyclamen and lilac note reminiscent of hydroxycitronellal, with strong tenacity; another listing gives floral, muguet, aldehydic and woody. A patent cites it as an IFF ingredient valued for its lily-of-the-valley note. Its EU status is taken from Regulation (EU) 2017/1410 as recorded in this site's regulatory notes.
- Leading note
- Muguet
- Clear facets
- Lily
- Supporting facets
- Cyclamen, lilac
- Character
- Soft, tenacious
What makes Lyral distinctive
The classic soft muguet aldehyde, now historical in EU cosmetics.
How Lyral is used
Formerly a backbone of muguet and white-floral accords; historic formulas name it, current EU cosmetics may not contain it.
Typical role: backbone (used in large proportions as a structural material of an accord).
How Lyral differs from similar materials
- Lilial
- Lilial, the other muguet aldehyde now prohibited in EU cosmetics, is more radiant, green and aldehydic-clean.
Each difference compares the published descriptions of the two materials. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.
Formulation considerations
Prohibited in cosmetic products in the European Union: Annex II, entry 1380 (Regulation (EU) 2017/1410), not to be placed on the market from 23 August 2019 or made available from 23 August 2021. IFRA restricts it (Amendment 49). It is a known skin sensitiser.
Identity and classification
- Type
- Aroma chemical
- Origin
- Synthetic
- Odour family
- Floral
- Note position
- Heart note
- Physical form at room temperature
- Viscous liquid
- Also known as
- HICC, Hydroxyisohexyl 3-cyclohexene carboxaldehyde
- CAS number
- 31906-04-4
- Molecular formula
- C13H22O2
- Molecular weight
- 210.31 g/mol
- IUPAC name
- 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde
The CAS number, formula and molecular weight are taken from PubChem compound 91604, whose own record lists this CAS number; checked 24 October 2026.
Safety and compliance
The IFRA Standards Library lists a Standard covering Lyral:
- "3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (HMPCC)" — Restriction, 49th Amendment, published 2020-01
Limits differ by product category and are set out in the Standard itself; this page does not reproduce them. The list above reflects the library as read on 19 October 2026.
Lyral is one of the 26 fragrance allergens listed individually in Annex III of the EU Cosmetics Regulation (label name: Hydroxyisohexyl 3-cyclohexene carboxaldehyde), which must be named on cosmetic labels above 0.001% in leave-on and 0.01% in rinse-off products. Regulation (EU) 2023/1545 extended the list; see the fragrance allergens list.
Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. It has a harmonised EU classification (Regulation (EC) No 1272/2008, Annex VI): H317 may cause an allergic skin reaction. Companies notifying the ECHA C&L Inventory classify it (1,981 reports): H317 may cause an allergic skin reaction (97.9% of reports); H412 harmful to aquatic life with long lasting effects (15.1% of reports). 41 of the reports find it does not meet the hazard criteria. A skin sensitiser classification concerns handling the neat material and the dose in a finished product; the IFRA Standards, where they apply, set the limits. Unless it is harmonised, this is the notifiers' own classification, not a binding one.
This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.
Materials it works with
Used in formulas and accords
Not currently used in any published formula.
The Formula & Accord Library lists Lyral here as soon as a published formula, accord or base uses it.
Further reading
Questions about Lyral
Is Lyral natural or synthetic?
Lyral is synthetic — it is made by chemical synthesis.
What is the CAS number of Lyral?
31906-04-4. It was checked against PubChem on 24 October 2026.
Is Lyral covered by an IFRA Standard?
Yes. The IFRA Standards Library lists a Standard covering it: "3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (HMPCC)" — Restriction, 49th Amendment. The limits depend on the product category; read the Standard itself before formulating.
Sources
- PubChem — compound 91604, checked 24 October 2026.
- PubChem — GHS classification (the ECHA C&L Inventory notifications and any harmonised EU entry), read 26 October 2026.
- IFRA — Standards Library, read 19 October 2026.
- EUR-Lex — Regulation (EC) No 1223/2009, Annex III.
- The Good Scents Company — Lyral — odour database.
- Commission Regulation (EU) 2017/1410 (copy on legislation.gov.uk) — regulatory record.
- US patent 10,597,605 — Composition having a muguet odor — published literature.
- Olfactory profile: the RUŌOD Lab team's synthesis of the published descriptions above, reviewed 24 October 2026. Evidence: more than one published description. Classification and the short description: revision 1. Descriptions of odour are judgement, not measurement.






