gamma-Dodecalactone

Aroma chemical · Fruity / Gourmand

peach, fatty, buttery, waxy — base note.

Aroma illustration for gamma-Dodecalactone: peaches, a wax candle and a block of butter, for its peach, fatty, waxy and buttery notes. It illustrates smell associations, not the material or its source.Skeletal formula of gamma-Dodecalactone (4-Dodecanolide), C12H22O2, drawn from PubChem's 2D record. Stereochemistry is not shown.
Aroma View: an illustration of what gamma-Dodecalactone smells like (peach, fatty, waxy, buttery), drawn by RUŌOD Lab — not its appearance or its source.Skeletal formula drawn by RUŌOD Lab from PubChem's 2D record (CID 16821). Stereochemistry is not shown; the coloured background is decoration.
Images

By the RUŌOD Lab TeamRevision 1Updated

In short

gamma-Dodecalactone is a lactone with a fatty, buttery peach odour. It is longer-lasting and fattier than gamma-undecalactone (aldehyde C-14).

What gamma-Dodecalactone smells like

gamma-Dodecalactone is a fatty, peachy lactone with a buttery, creamy edge. The Good Scents Company lists fatty, peach, sweet, metallic and fruity; ChemicalBook fatty, peachy and somewhat musky, with a buttery, peach-like flavour; Bedoukian waxy, fatty and sweet with green, rind-like undertones that add warmth and creaminess. Arctander, as quoted, recommends it for fruity-fatty top notes and long tenacity in heavy florals and powdery types.

Leading note
Fatty peach
Clear facets
Buttery, creamy
Supporting facets
Waxy
Faint facets
Musky, metallic
Character
Rich, fatty, tenacious, warm
  • peach
  • fatty
  • buttery
  • waxy

What makes gamma-Dodecalactone distinctive

The heaviest of the gamma peach lactones: more butter and wax than fruit, and the longest-lasting.

How gamma-Dodecalactone is used

Used for a lasting, fatty-fruity warmth in heavy florals and powdery compositions, and in peach, apricot and creamy accords and dairy flavours.

Typical role: modifier (used in small amounts to change the character of a blend); fixative (slow to evaporate; helps a blend last and holds lighter notes).

How gamma-Dodecalactone differs from similar materials

gamma-Decalactone
gamma-Decalactone is the brighter, fresher peach-apricot; the dodecalactone is richer, fattier and longer-lasting. (compared directly by a cited source)
gamma-Undecalactone (Aldehyde C-14)
Aldehyde C-14 is the more fruity, classic peach; the dodecalactone is fattier and more buttery.
delta-Dodecalactone
delta-Dodecalactone is creamier and more coconut-butter; the gamma isomer is a fatty peach.

An asterisk marks a difference that a cited source states directly. The others compare the published descriptions of each material. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.

Identity and classification

Type
Aroma chemical
Origin
Occurs in nature
Odour family
Fruity / Gourmand
Note position
Base note
Physical form at room temperature
Liquid
Also known as
4-Dodecanolide
CAS number
2305-05-7
Molecular formula
C12H22O2
Molecular weight
198.3 g/mol
IUPAC name
5-octyloxolan-2-one

The CAS number, formula and molecular weight are taken from PubChem compound 16821, whose own record lists this CAS number; checked 19 October 2026.

Safety and compliance

Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. Companies notifying the ECHA C&L Inventory report it as not meeting the GHS hazard criteria (1,615 of 1,683 reports). Unless it is harmonised, this is the notifiers' own classification, not a binding one.

This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.

Materials it works with

Used in formulas and accords

Used in 2 published formulas

gamma-Dodecalactone is an ingredient in 2 perfume formulas in the Formula & Accord Library.

RUŌOD House Originals

Original compositions by RUŌOD House.

Further reading

Questions about gamma-Dodecalactone

Is gamma-Dodecalactone natural or synthetic?

The molecule occurs in nature. Commercial gamma-Dodecalactone may be made by synthesis or obtained from natural sources, so check the supplier's specification if the distinction matters to you.

What is the CAS number of gamma-Dodecalactone?

2305-05-7. It was checked against PubChem on 19 October 2026.

Which published formulas use gamma-Dodecalactone?

gamma-Dodecalactone is used in 2 published formulas in the RUŌOD Lab Formula & Accord Library: Gardenia Milk and Osmanthus Suede. Each is listed with a link under "Used in formulas and accords" on this page.

Sources

Your own records, next to the reference

Keep your own record of gamma-Dodecalactone — supplier, cost, stock, dilutions and where it is used — in RUŌOD Lab's material library.