Isomenthone

Aroma chemical · Aromatic / Green

minty, peppermint — top note.

Aroma illustration for Isomenthone: mint leaves, for its minty and peppermint notes. It illustrates smell associations, not the material or its source.Skeletal formula of Isomenthone (p-Menthan-3-one, cis), C10H18O, drawn from PubChem's 2D record. Stereochemistry is not shown.
Aroma View: an illustration of what Isomenthone smells like (minty, peppermint), drawn by RUŌOD Lab — not its appearance or its source.Skeletal formula drawn by RUŌOD Lab from PubChem's 2D record (CID 6432469). Stereochemistry is not shown; the coloured background is decoration.
Images

By the RUŌOD Lab TeamRevision 1Updated

In short

Isomenthone is the cis isomer of menthone, a p-menthane ketone found in mint and geranium oils. JECFA describes it as having a peppermint odour.

What Isomenthone smells like

JECFA, as published by PubChem, describes isomenthone as a colourless, slightly oily liquid with a peppermint odour. Parchem's specification for the racemic material gives a mentholic, cooling, minty and camphoraceous odour with a refreshing, ethereal lift.

Leading note
Peppermint
Character
Cool
  • minty
  • peppermint

What makes Isomenthone distinctive

The peppermint odour of menthone's isomer, as JECFA gives it.

How Isomenthone is used

Used in mint and herbal accords and in geranium and rose reconstitutions.

Typical role: modifier (used in small amounts to change the character of a blend).

How Isomenthone differs from similar materials

Peppermint Oil
Peppermint oil is a whole oil, menthol's chill over a sweet herbal body; isomenthone is a single minty ketone, peppermint-like with a camphoraceous lift.

Each difference compares the published descriptions of the two materials. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.

Formulation considerations

A stereoisomer of menthone and a different molecule from it; the two are not interchangeable.

Identity and classification

Type
Aroma chemical
Origin
Occurs in nature
Odour family
Aromatic / Green
Note position
Top note
Physical form at room temperature
Liquid
Also known as
p-Menthan-3-one, cis
CAS number
491-07-6
Molecular formula
C10H18O
Molecular weight
154.25 g/mol
IUPAC name
cis-(2S,5S)-5-methyl-2-propan-2-ylcyclohexan-1-one

The CAS number, formula and molecular weight are taken from PubChem compound 6432469, whose own record lists this CAS number; checked 24 October 2026.

Safety and compliance

Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. Companies notifying the ECHA C&L Inventory classify it (1,631 reports): H315 causes skin irritation (88.8% of reports); H317 may cause an allergic skin reaction (88.8% of reports). 87 of the reports find it does not meet the hazard criteria. A skin sensitiser classification concerns handling the neat material and the dose in a finished product; the IFRA Standards, where they apply, set the limits. Unless it is harmonised, this is the notifiers' own classification, not a binding one.

This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.

Materials it works with

Used in formulas and accords

Used in 1 published formula

Isomenthone is an ingredient in 1 perfume formula in the Formula & Accord Library.

Further reading

Questions about Isomenthone

Is Isomenthone natural or synthetic?

The molecule occurs in nature. Commercial Isomenthone may be made by synthesis or obtained from natural sources, so check the supplier's specification if the distinction matters to you.

What is the CAS number of Isomenthone?

491-07-6. It was checked against PubChem on 24 October 2026.

Which published formulas use Isomenthone?

Isomenthone is used in 1 published formula in the RUŌOD Lab Formula & Accord Library: Hindi Maliki Qadeem. Each is listed with a link under "Used in formulas and accords" on this page.

Sources

Your own records, next to the reference

Keep your own record of Isomenthone — supplier, cost, stock, dilutions and where it is used — in RUŌOD Lab's material library.