In short
Isomenthone is the cis isomer of menthone, a p-menthane ketone found in mint and geranium oils. JECFA describes it as having a peppermint odour.
What Isomenthone smells like
JECFA, as published by PubChem, describes isomenthone as a colourless, slightly oily liquid with a peppermint odour. Parchem's specification for the racemic material gives a mentholic, cooling, minty and camphoraceous odour with a refreshing, ethereal lift.
- Leading note
- Peppermint
- Character
- Cool
What makes Isomenthone distinctive
The peppermint odour of menthone's isomer, as JECFA gives it.
How Isomenthone is used
Used in mint and herbal accords and in geranium and rose reconstitutions.
Typical role: modifier (used in small amounts to change the character of a blend).
How Isomenthone differs from similar materials
- Peppermint Oil
- Peppermint oil is a whole oil, menthol's chill over a sweet herbal body; isomenthone is a single minty ketone, peppermint-like with a camphoraceous lift.
Each difference compares the published descriptions of the two materials. Smell varies with grade, supplier and dilution; compare them side by side on blotters before substituting one for another.
Formulation considerations
A stereoisomer of menthone and a different molecule from it; the two are not interchangeable.
Identity and classification
- Type
- Aroma chemical
- Origin
- Occurs in nature
- Odour family
- Aromatic / Green
- Note position
- Top note
- Physical form at room temperature
- Liquid
- Also known as
- p-Menthan-3-one, cis
- CAS number
- 491-07-6
- Molecular formula
- C10H18O
- Molecular weight
- 154.25 g/mol
- IUPAC name
- cis-(2S,5S)-5-methyl-2-propan-2-ylcyclohexan-1-one
The CAS number, formula and molecular weight are taken from PubChem compound 6432469, whose own record lists this CAS number; checked 24 October 2026.
Safety and compliance
Hazard classification of the neat substance, as PubChem summarises it, read 26 October 2026. Companies notifying the ECHA C&L Inventory classify it (1,631 reports): H315 causes skin irritation (88.8% of reports); H317 may cause an allergic skin reaction (88.8% of reports). 87 of the reports find it does not meet the hazard criteria. A skin sensitiser classification concerns handling the neat material and the dose in a finished product; the IFRA Standards, where they apply, set the limits. Unless it is harmonised, this is the notifiers' own classification, not a binding one.
This page is general information, not a safety assessment or a specification. Confirm identity, composition, IFRA status and allergen content from your supplier's documents for the lot you hold.
Materials it works with
Used in formulas and accords
Used in 1 published formula
Isomenthone is an ingredient in 1 perfume formula in the Formula & Accord Library.
Further reading
Questions about Isomenthone
Is Isomenthone natural or synthetic?
The molecule occurs in nature. Commercial Isomenthone may be made by synthesis or obtained from natural sources, so check the supplier's specification if the distinction matters to you.
What is the CAS number of Isomenthone?
491-07-6. It was checked against PubChem on 24 October 2026.
Which published formulas use Isomenthone?
Isomenthone is used in 1 published formula in the RUŌOD Lab Formula & Accord Library: Hindi Maliki Qadeem. Each is listed with a link under "Used in formulas and accords" on this page.
Sources
- PubChem — compound 6432469, checked 24 October 2026.
- PubChem — GHS classification (the ECHA C&L Inventory notifications and any harmonised EU entry), read 26 October 2026.
- PubChem — isomenthone (JECFA description) (CID 6432469) — odour database.
- Parchem — (±)-isomenthone specification — distributor's description.
- Olfactory profile: the RUŌOD Lab team's synthesis of the published descriptions above, reviewed 26 October 2026. Evidence: more than one published description. Classification and the short description: revision 1. Descriptions of odour are judgement, not measurement.






